High Protein Pasta Bake

Featured in: Cozy Dinner Plates

This dish combines al dente pasta with lean ground beef, turkey pepperoni, and a rich, creamy sauce made from Greek yogurt, mozzarella, and Parmesan cheeses. Sautéed vegetables like onion, garlic, bell pepper, and mushrooms add depth to the hearty meat sauce, which is baked with extra cheese and pepperoni topping until golden and bubbly. The meal offers a satisfying balance of flavors and textures, ideal for an easy, nourishing main course served warm and garnished with fresh herbs.

Updated on Thu, 12 Feb 2026 23:50:40 GMT
High-protein pizza pasta bake with lean beef, pepperoni, and creamy yogurt-cheese sauce baked until bubbly and golden. Save
High-protein pizza pasta bake with lean beef, pepperoni, and creamy yogurt-cheese sauce baked until bubbly and golden. | frizplo.com

Imagine the irresistible aroma of bubbling cheese and savory meat filling your kitchen. This High-Protein Pizza Pasta Bake brings together two beloved comfort foods - pizza and pasta - in one satisfying, protein-packed dish. With lean ground beef, pepperoni, and a creamy Greek yogurt cheese sauce, this hearty casserole delivers all the flavors of pizza in a fork-friendly format that's perfect for family dinners or meal prep.

High-protein pizza pasta bake with lean beef, pepperoni, and creamy yogurt-cheese sauce baked until bubbly and golden. Save
High-protein pizza pasta bake with lean beef, pepperoni, and creamy yogurt-cheese sauce baked until bubbly and golden. | frizplo.com

This pasta bake transforms classic pizza night into a more substantial meal that'll fuel your body and satisfy your taste buds. The protein-enriched pasta combined with lean beef and Greek yogurt creates a balanced meal that's as nutritious as it is delicious. The cheesy, golden top layer hides a protein-rich base that makes this dish perfect for athletes, growing families, or anyone looking to add more protein to their diet without sacrificing flavor.

Ingredients

  • 12 oz (340 g) high-protein penne or rotini pasta
  • 8 oz (225 g) lean ground beef
  • 2 oz (55 g) turkey or regular pepperoni, sliced
  • 1 medium onion, finely chopped
  • 2 cloves garlic, minced
  • 1 bell pepper, diced (optional)
  • 1 cup (150 g) sliced mushrooms (optional)
  • 2 cups (480 ml) low-sodium marinara sauce
  • 1 cup (240 g) plain Greek yogurt (2% or fat-free)
  • 1 cup (110 g) part-skim shredded mozzarella cheese
  • ¼ cup (25 g) grated Parmesan cheese
  • ½ tsp dried oregano
  • ½ tsp dried basil
  • ¼ tsp crushed red pepper flakes (optional)
  • Salt and black pepper, to taste
  • ½ cup (55 g) part-skim shredded mozzarella cheese, for topping
  • 1 oz (28 g) pepperoni, extra, for topping
  • Fresh basil or parsley, chopped (optional)
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Instructions

Prepare the oven and pasta
Preheat oven to 375°F (190°C). Grease a 9x13-inch (23x33 cm) baking dish. Cook pasta in a large pot of salted boiling water until just al dente. Drain and set aside.
Cook the meat and vegetables
In a large skillet over medium heat, cook ground beef, breaking it up, until browned and cooked through. Add onion and cook 3–4 minutes until softened. Stir in garlic, bell pepper, and mushrooms; sauté another 3 minutes. Drain excess fat if needed.
Prepare the sauce
Stir in marinara sauce, oregano, basil, and red pepper flakes. Simmer for 5 minutes. Season with salt and pepper.
Make the cheese mixture
In a bowl, whisk together Greek yogurt, 1 cup mozzarella, and Parmesan until smooth.
Combine and assemble
In a large mixing bowl, combine cooked pasta, beef-vegetable sauce, sliced pepperoni, and yogurt-cheese mixture. Toss well to coat. Transfer mixture to prepared baking dish. Top with remaining ½ cup mozzarella and extra pepperoni slices.
Bake and serve
Bake uncovered for 20 minutes, until bubbly and golden. Let rest 5 minutes before garnishing with fresh basil or parsley. Serve warm.

Zusatztipps für die Zubereitung

Für ein optimales Ergebnis, kochen Sie die Pasta etwas weniger als al dente, da sie beim Backen weiter gart. Um Zeit zu sparen, können Sie das Fleisch und die Sauce bereits am Vortag zubereiten und im Kühlschrank aufbewahren. Achten Sie beim Anrichten in der Auflaufform darauf, dass die Oberfläche gleichmäßig mit Käse bedeckt ist, damit jede Portion eine schöne, goldbraune Kruste erhält.

Varianten und Anpassungen

Dieses Rezept lässt sich leicht an verschiedene Ernährungsbedürfnisse anpassen. Für eine vegetarische Version können Sie das Fleisch durch 2 Tassen gekochte Linsen oder gewürfelten Tofu ersetzen. Verwenden Sie glutenfreie Pasta für eine glutenfreie Option. Probieren Sie auch verschiedene Gemüsesorten wie Zucchini, Spinat oder Oliven hinzuzufügen, um den Nährwert weiter zu erhöhen. Für eine keto-freundlichere Variante, reduzieren Sie die Pastamenge und erhöhen Sie den Anteil an Fleisch und Gemüse.

Serviervorschläge

Servieren Sie diesen proteinreichen Auflauf mit einem frischen grünen Salat für ein ausgewogenes Abendessen. Eine Scheibe Knoblauchbrot eignet sich hervorragend zum Auftunken der leckeren Sauce. Für eine festlichere Mahlzeit passt ein trockener italienischer Rotwein wie Chianti oder Montepulciano hervorragend dazu. Die Reste können Sie bis zu 3 Tage im Kühlschrank aufbewahren und portionsweise aufwärmen oder für ein schnelles Mittagessen mitnehmen.

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| frizplo.com

Whether you're feeding a hungry family, meal prepping for a protein-rich week, or just craving the comfort of pizza in a heartier form, this High-Protein Pizza Pasta Bake delivers on all fronts. The combination of lean proteins, complex carbohydrates, and vegetables creates a balanced meal that satisfies both nutritional needs and comfort food cravings. With its make-ahead potential and leftovers that taste even better the next day, this dish is bound to become a regular in your meal rotation.

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Recipe FAQ

Can I substitute the ground beef with another meat?

Yes, ground turkey or chicken can be used as alternatives for a leaner protein option while maintaining flavor and texture.

Is it possible to add more vegetables to the bake?

Absolutely, spinach, zucchini, or olives can be added to incorporate more nutrients and enhance the dish’s flavor profile.

What type of pasta works best for this bake?

Penne or rotini pasta hold sauces well and maintain their texture during baking, but whole-wheat or chickpea pasta are great for added fiber and protein.

How do I prevent the bake from becoming too watery?

Drain the cooked pasta thoroughly, and simmer the sauce to reduce excess moisture before combining with other ingredients for baking.

Can I prepare this dish in advance?

Yes, assemble the bake ahead of time and refrigerate it, then bake just before serving to enjoy fresh, melty results.

High Protein Pasta Bake

A protein-packed bake blending lean beef, pepperoni, and creamy yogurt-cheese sauce with pasta.

Prep duration
20 min
Time to cook
30 min
Complete duration
50 min
Created by Madison Young

Classification Cozy Dinner Plates

Complexity Level Easy

Cultural Origin American-Italian

Output 6 Portion Count

Dietary requirements None specified

Components

Pasta

01 12 oz high-protein penne or rotini pasta

Meats

01 8 oz lean ground beef
02 2 oz turkey or regular pepperoni, sliced

Vegetables & Aromatics

01 1 medium onion, finely chopped
02 2 cloves garlic, minced
03 1 bell pepper, diced
04 1 cup sliced mushrooms

Sauce

01 2 cups low-sodium marinara sauce
02 1 cup plain Greek yogurt, 2% or fat-free
03 1 cup part-skim shredded mozzarella cheese
04 ¼ cup grated Parmesan cheese
05 ½ teaspoon dried oregano
06 ½ teaspoon dried basil
07 ¼ teaspoon crushed red pepper flakes
08 Salt and black pepper to taste

Topping

01 ½ cup part-skim shredded mozzarella cheese
02 1 oz pepperoni, extra, for topping
03 Fresh basil or parsley, chopped

Directions

Step 01

Prepare Baking Dish: Preheat oven to 375°F. Grease a 9x13-inch baking dish and set aside.

Step 02

Cook Pasta: Cook pasta in a large pot of salted boiling water until just al dente. Drain and set aside.

Step 03

Brown Beef and Aromatics: In a large skillet over medium heat, cook ground beef, breaking it up, until browned and cooked through. Add chopped onion and cook 3-4 minutes until softened. Stir in minced garlic, diced bell pepper, and sliced mushrooms; sauté for another 3 minutes.

Step 04

Simmer Sauce: Stir in marinara sauce, dried oregano, dried basil, and crushed red pepper flakes. Simmer for 5 minutes. Season with salt and black pepper to taste. Drain excess fat if needed.

Step 05

Prepare Cheese Mixture: In a bowl, whisk together Greek yogurt, 1 cup mozzarella cheese, and Parmesan cheese until smooth and well combined.

Step 06

Combine Ingredients: In a large mixing bowl, combine cooked pasta, beef-vegetable sauce, sliced pepperoni, and yogurt-cheese mixture. Toss well to coat all components evenly.

Step 07

Assemble in Baking Dish: Transfer mixture to prepared baking dish. Top with remaining ½ cup mozzarella cheese and extra pepperoni slices.

Step 08

Bake Until Golden: Bake uncovered for 20 minutes, until bubbly and golden brown.

Step 09

Rest and Garnish: Let rest for 5 minutes before garnishing with fresh basil or parsley. Serve warm.

Necessary tools

  • Large pot
  • Large skillet
  • Mixing bowls
  • 9x13-inch baking dish
  • Whisk
  • Spatula

Allergy details

Review each component for potential allergens and seek professional healthcare advice if you're uncertain.
  • Contains wheat from pasta
  • Contains milk from cheese and yogurt
  • Possible sulfites in pepperoni
  • Check labels for gluten-free pasta and nitrate-free pepperoni alternatives

Nutritional breakdown (per portion)

These values are provided as estimates only and shouldn't replace professional medical guidance.
  • Energy Content: 410
  • Fats: 13 g
  • Carbohydrates: 40 g
  • Proteins: 31 g