Cajun Chicken Pasta Bake

Featured in: Cozy Dinner Plates

This vibrant casserole combines tender chicken pieces coated in spicy Cajun seasonings with softened bell peppers and onion. Cream and milk create a smooth sauce melted with mozzarella, cheddar, and Parmesan cheeses. Mixed with perfectly cooked pasta, the dish is baked until bubbly and golden, then garnished with fresh parsley. It offers a rich, comforting experience with a balance of spice and creaminess ideal for gatherings or cozy dinners.

Updated on Sat, 15 Nov 2025 15:17:00 GMT
Cajun Chicken Pasta Bake, a bubbly casserole topped with melted cheese, promising a spicy, creamy bite. Save
Cajun Chicken Pasta Bake, a bubbly casserole topped with melted cheese, promising a spicy, creamy bite. | frizplo.com

A vibrant comforting casserole featuring tender chicken spicy Cajun seasonings creamy sauce and melty cheese all baked with pasta for a crowd-pleasing meal.

The first time I made this Cajun chicken pasta bake it quickly became a go-to weekday recipe. My family loves the balance of spice creamy sauce and gooey cheese with every bite.

Ingredients

  • Chicken breasts: 2 large, cut into bite-sized pieces
  • Red bell pepper: 1, diced
  • Yellow bell pepper: 1, diced
  • Red onion: 1 small, diced
  • Garlic: 2 cloves, minced
  • Penne or rigatoni pasta: 300 g (10 oz)
  • Olive oil: 2 tbsp
  • Butter: 1 tbsp
  • Heavy cream: 200 ml (¾ cup)
  • Milk: 120 ml (½ cup)
  • Mozzarella cheese: 100 g (1 cup), shredded
  • Parmesan cheese: 50 g (½ cup), grated
  • Cheddar cheese: 100 g (1 cup), shredded
  • Cajun seasoning: 1½ tbsp (plus extra for garnish)
  • Smoked paprika: ½ tsp
  • Salt: ½ tsp
  • Black pepper: ¼ tsp
  • Chili flakes (optional): ¼ tsp, for extra heat
  • Fresh parsley: 2 tbsp, chopped

Instructions

Preheat:
Preheat your oven to 200°C (400°F).
Cook Pasta:
Cook pasta in salted boiling water 2 minutes less than package instructions as it will finish cooking in the oven. Drain and set aside.
Cook Chicken:
In a large skillet heat olive oil and butter over medium-high heat. Add chicken 1 tbsp Cajun seasoning salt and pepper. Sauté until browned and cooked through about 6–8 minutes. Remove chicken and set aside.
Sauté Vegetables:
In the same skillet add onions and bell peppers. Cook for 4–5 minutes until softened. Add garlic smoked paprika and chili flakes (if using) and sauté for 1 minute.
Prepare Sauce:
Reduce heat to medium. Pour in cream and milk stirring to scrape up any browned bits. Simmer for 2–3 minutes.
Add Cheese:
Add ¾ of the mozzarella cheddar and Parmesan to the sauce. Stir until melted and smooth.
Combine:
Return the chicken to the skillet then add the cooked pasta. Toss everything together to coat well. Adjust seasoning with extra Cajun spice salt or pepper if needed.
Transfer and Top:
Transfer mixture to a lightly greased baking dish. Sprinkle remaining cheeses over the top.
Bake:
Bake for 18–20 minutes until cheese is golden and bubbly.
Garnish and Serve:
Garnish with chopped parsley and a pinch of Cajun seasoning before serving.
Golden-browned Cajun Chicken Pasta Bake with a creamy sauce, vegetables, and perfectly cooked pasta ready to serve. Save
Golden-browned Cajun Chicken Pasta Bake with a creamy sauce, vegetables, and perfectly cooked pasta ready to serve. | frizplo.com

We made this pasta bake for a Sunday dinner and everyone went back for seconds. It's become a favorite for potlucks and family gatherings.

Serving Suggestions

Enjoy with a crisp green salad or garlic bread for a well-rounded meal. This dish pairs nicely with Sauvignon Blanc or iced tea for a refreshing balance to the spice.

Allergen Information

This recipe contains milk (cheese cream butter) and wheat (pasta). Use gluten-free pasta for a gluten-free option and always verify labels for potential allergens.

Storage & Reheating

Store leftovers covered in the refrigerator for up to 3 days. Reheat in the oven at 180°C (350°F) until warmed through or microwave individual portions as needed.

A close-up view of the flavorful Cajun Chicken Pasta Bake, showcasing the melted cheese and herbs on top. Save
A close-up view of the flavorful Cajun Chicken Pasta Bake, showcasing the melted cheese and herbs on top. | frizplo.com

This crowd-pleasing casserole is sure to warm your table and bring smiles at dinner time. Enjoy every creamy spicy cheesy bite.

Recipe FAQ

What pasta types work best for this dish?

Penne or rigatoni are ideal as their shape holds the sauce well, but other sturdy pasta can be substituted.

Can the spice level be adjusted?

Yes, reduce or omit chili flakes and Cajun seasoning to suit milder preferences.

Is it possible to make this dish lighter?

Using half-and-half instead of heavy cream reduces richness while keeping creaminess.

How do I ensure the chicken stays tender?

Sauté chicken pieces until browned but avoid overcooking; the baking finishes cooking gently.

Can additional vegetables be added?

Sliced mushrooms or spinach can be incorporated for extra texture and flavor.

What are good serving suggestions?

Serve alongside a fresh salad or garlic bread; pairs well with crisp white wine or iced tea.

Cajun Chicken Pasta Bake

Tender chicken and spicy Cajun-seasoned pasta baked with creamy cheese for a comforting meal.

Prep duration
20 min
Time to cook
35 min
Complete duration
55 min
Created by Madison Young

Classification Cozy Dinner Plates

Complexity Level Medium

Cultural Origin American (Cajun-inspired)

Output 4 Portion Count

Dietary requirements None specified

Components

Meats

01 2 large chicken breasts, cut into bite-sized pieces

Vegetables

01 1 red bell pepper, diced
02 1 yellow bell pepper, diced
03 1 small red onion, diced
04 2 cloves garlic, minced

Pasta

01 10 ounces penne or rigatoni pasta

Sauces & Dairy

01 2 tablespoons olive oil
02 1 tablespoon butter
03 ¾ cup heavy cream
04 ½ cup milk
05 1 cup shredded mozzarella cheese
06 ½ cup grated Parmesan cheese
07 1 cup shredded cheddar cheese

Spices & Seasonings

01 1½ tablespoons Cajun seasoning, plus extra for garnish
02 ½ teaspoon smoked paprika
03 ½ teaspoon salt
04 ¼ teaspoon black pepper
05 ¼ teaspoon chili flakes (optional)

Garnish

01 2 tablespoons chopped fresh parsley

Directions

Step 01

Preheat oven: Preheat oven to 400°F.

Step 02

Cook pasta: Boil pasta in salted water until 2 minutes under al dente, then drain and set aside.

Step 03

Sauté chicken: Heat olive oil and butter in a large skillet over medium-high heat. Season chicken with 1 tablespoon Cajun seasoning, salt, and pepper. Cook until browned and cooked through, about 6 to 8 minutes. Remove chicken and set aside.

Step 04

Cook vegetables: In the same skillet, sauté diced onion and bell peppers for 4 to 5 minutes until softened. Add garlic, smoked paprika, and chili flakes if using; cook for 1 more minute.

Step 05

Prepare sauce: Lower heat to medium. Pour in heavy cream and milk, stirring frequently to incorporate browned bits. Simmer for 2 to 3 minutes.

Step 06

Melt cheeses: Add three-quarters of the mozzarella, cheddar, and Parmesan cheeses to the sauce. Stir until fully melted and smooth.

Step 07

Combine ingredients: Return chicken to the skillet, add cooked pasta, and toss to evenly coat. Adjust seasoning with extra Cajun seasoning, salt, or pepper if needed.

Step 08

Assemble bake: Transfer mixture to a greased 2-quart baking dish. Sprinkle remaining cheese over the top.

Step 09

Bake: Bake uncovered for 18 to 20 minutes, or until cheese is golden and bubbling.

Step 10

Garnish and serve: Sprinkle chopped fresh parsley and a pinch of Cajun seasoning over the top before serving.

Necessary tools

  • Large skillet or sauté pan
  • Medium saucepan for pasta
  • 2-quart baking dish
  • Wooden spoon
  • Chef's knife and cutting board

Allergy details

Review each component for potential allergens and seek professional healthcare advice if you're uncertain.
  • Contains milk and wheat; may contain gluten and cross-contamination in spice blends

Nutritional breakdown (per portion)

These values are provided as estimates only and shouldn't replace professional medical guidance.
  • Energy Content: 670
  • Fats: 32 g
  • Carbohydrates: 56 g
  • Proteins: 40 g